REGULAR CONTENT
Final ID
617
Type
Educational Exhibit-Poster Only
Authors
L Pung1, M Ahmad2, K Mueller2, J Rosenberg2, C Stave3, G Hwang4, R Shah4, N Kothary4
Institutions
1Siemens Healthcare, Malvern, PA, 2Stanford University School of Medicine, Stanford, CA, 3Lane Medical Library, Stanford University, Stanford, CA, 4Stanford Healthcare, Stanford, CA
Purpose
To review the available evidence in the use of cone-beam CT (CBCT) during transcatheter arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) for detection of tumor and feeding arteries.
Materials & Methods
Literature searches were conducted from inception to May 15, 2016 in PubMed (includes MEDLINE), SCOPUS and the Cochrane Central Register of Controlled Trials. Search terms included 'cone beam,' 'CBCT,' 'c-arm,' 'CACT,' 'cone-beam CT', 'volumetric CT,' 'volume computed tomography,' 'volume CT,' AND 'liver,' 'hepatic*,' 'hepatoc*'. Full search strategies available on request. Studies that involved adult populations with only HCC treated via TACE utilizing CBCT were included.
Results
Eighteen studies were found to fit the inclusion criteria. Pooled sensitivity of CBCT for detecting tumor was 90% (95% CI 82-95%), whereas the pooled sensitivity of digital subtraction angiography (DSA) for tumor detection was 67% (95% CI 51-80%). The pooled sensitivity of CBCT for detecting tumor feeding arteries was 93% (95% CI 91%-95%) whereas the pooled sensitivity of DSA was 55% (95% CI 36-74%).
Conclusions
CBCT can significantly increase the detection of tumors and tumor feeding arteries during TACE. Consideration should be given to utilization of CBCT as an adjunct tool to DSA in TACE treatments of HCC.
Final ID
617
Type
Educational Exhibit-Poster Only
Authors
L Pung1, M Ahmad2, K Mueller2, J Rosenberg2, C Stave3, G Hwang4, R Shah4, N Kothary4
Institutions
1Siemens Healthcare, Malvern, PA, 2Stanford University School of Medicine, Stanford, CA, 3Lane Medical Library, Stanford University, Stanford, CA, 4Stanford Healthcare, Stanford, CA
Purpose
To review the available evidence in the use of cone-beam CT (CBCT) during transcatheter arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) for detection of tumor and feeding arteries.
Materials & Methods
Literature searches were conducted from inception to May 15, 2016 in PubMed (includes MEDLINE), SCOPUS and the Cochrane Central Register of Controlled Trials. Search terms included 'cone beam,' 'CBCT,' 'c-arm,' 'CACT,' 'cone-beam CT', 'volumetric CT,' 'volume computed tomography,' 'volume CT,' AND 'liver,' 'hepatic*,' 'hepatoc*'. Full search strategies available on request. Studies that involved adult populations with only HCC treated via TACE utilizing CBCT were included.
Results
Eighteen studies were found to fit the inclusion criteria. Pooled sensitivity of CBCT for detecting tumor was 90% (95% CI 82-95%), whereas the pooled sensitivity of digital subtraction angiography (DSA) for tumor detection was 67% (95% CI 51-80%). The pooled sensitivity of CBCT for detecting tumor feeding arteries was 93% (95% CI 91%-95%) whereas the pooled sensitivity of DSA was 55% (95% CI 36-74%).
Conclusions
CBCT can significantly increase the detection of tumors and tumor feeding arteries during TACE. Consideration should be given to utilization of CBCT as an adjunct tool to DSA in TACE treatments of HCC.