REGULAR CONTENT
Final ID
506
Type
Original Scientific Research-Oral or Pos
Authors
S Wagner1, A Kim2, G Lynskey3, T Caridi4, D Buckley5
Institutions
1Georgetown University School of Medicine, Washington, DC, 2Medstar Georgetown University Hospital, Washington, DC, 3Georgetown University Hospital, Arlington, VA, 4Georgetown University Hospital, Washington, DC, 5N/A, Gaithersburg, MD
Purpose
To assess for correlation between liver tumor volume and degree of hypertrophy of the contralateral lobe achieved after Y90 treatment.
Materials & Methods
Retrospective chart review of all patients undergoing right hepatic lobe Y90 RE in the past 5 years. Patients without follow-up imaging (1-6 months) post-embolization were excluded from the study. Additional exclusion criteria included documented left lobe disease and left lobe treatment within 6 months pre or post-right lobe treatment. Liver volume measurements of the right lobe, left lobe, and left lateral segments were made both pre- and post-Y90 RE.
Results
160 patients were identified having undergone right lobe Y90 RE within the last 5 years. Of these, 147 were excluded for various reasons including left lobe disease, left lobe treatment with Y90 and lack of follow-up imaging. 13 patients that were evaluated: 11 male and 2 female. There were 8 cases of HCC, 3 cases of pancreatic adenocarcinoma, 1 case of cholangiocarcinoma, and 1 case of colorectal adenocarcinoma. Results are shown in table 1.
Conclusions
We found no direct correlation between right lobe tumor burden and left lobar hypertrophy in patients undergoing right lobe Y90 radioembolization. Radioembolization is a valid option to induce left lobe hypertrophy regardless of right lobe disease burden. Further evaluations are needed to confirm our findings.
Final ID
506
Type
Original Scientific Research-Oral or Pos
Authors
S Wagner1, A Kim2, G Lynskey3, T Caridi4, D Buckley5
Institutions
1Georgetown University School of Medicine, Washington, DC, 2Medstar Georgetown University Hospital, Washington, DC, 3Georgetown University Hospital, Arlington, VA, 4Georgetown University Hospital, Washington, DC, 5N/A, Gaithersburg, MD
Purpose
To assess for correlation between liver tumor volume and degree of hypertrophy of the contralateral lobe achieved after Y90 treatment.
Materials & Methods
Retrospective chart review of all patients undergoing right hepatic lobe Y90 RE in the past 5 years. Patients without follow-up imaging (1-6 months) post-embolization were excluded from the study. Additional exclusion criteria included documented left lobe disease and left lobe treatment within 6 months pre or post-right lobe treatment. Liver volume measurements of the right lobe, left lobe, and left lateral segments were made both pre- and post-Y90 RE.
Results
160 patients were identified having undergone right lobe Y90 RE within the last 5 years. Of these, 147 were excluded for various reasons including left lobe disease, left lobe treatment with Y90 and lack of follow-up imaging. 13 patients that were evaluated: 11 male and 2 female. There were 8 cases of HCC, 3 cases of pancreatic adenocarcinoma, 1 case of cholangiocarcinoma, and 1 case of colorectal adenocarcinoma. Results are shown in table 1.
Conclusions
We found no direct correlation between right lobe tumor burden and left lobar hypertrophy in patients undergoing right lobe Y90 radioembolization. Radioembolization is a valid option to induce left lobe hypertrophy regardless of right lobe disease burden. Further evaluations are needed to confirm our findings.