REGULAR CONTENT
Final ID
477
Type
Original Scientific Research-Oral or Pos
Authors
N Shah1, P Zeni2, H Dalsania3, D Mobley4, J Weintraub5
Institutions
1Columbia University Medical Center, New York, NY, 2Memphis Interventional Radiology Clinic, Memphis, TN, 3N/A, Cordova, TN, 4N/A, Brooklyn, NY, 5N/A, Scarsdale, NY
Purpose
Determine the efficacy of FoxHollow Silverhawk Atherectomy Device at obtaining a tissue diagnosis in the setting of malignant biliary strictures.
Materials & Methods
Eighty-one biopsies in seventy-nine patients with malignant biliary strictures underwent percutaneous biliary cholangiography. After cannulation of the biliary system, the Foxhollow Silverhawk device was used to obtain multiple biliary shavings, which were then sent for cytology and staining.Additional studies involving complex hepatobiliary and transplant cases were later included to determine this technique's utility in these clinical settings.
Results
A total of eighty-one biopsies were performed on seventy-nine patients after successful percutaneous transhepatic cholangiography and cannulation of the biliary system, using the Foxhollow Silverhawk Device. 39 of the participants were male while 40 were female. The participants also demonstrated an age range of 43-93 years, which corresponded to an average age of 70.6 years. A right approach to the biliary system was favored over the left at a rate of 77/81 or 95%.The results of this study yielded a sensitivity of 93% and a specificity of 100%. A positive predictive value of 100% and a negative predictive value of 64% were also demonstrated in this study. Of the false negative biopsies, all five were taken from the distal common bile duct. These false negatives were later diagnosed at surgery.
Conclusions
With a sensitivity of 93% and a specificity of 100%, the Foxhollow Silverhawk Atherectomy Device is a formidable option for tissue diagnosis in malignant biliary strictures.
Final ID
477
Type
Original Scientific Research-Oral or Pos
Authors
N Shah1, P Zeni2, H Dalsania3, D Mobley4, J Weintraub5
Institutions
1Columbia University Medical Center, New York, NY, 2Memphis Interventional Radiology Clinic, Memphis, TN, 3N/A, Cordova, TN, 4N/A, Brooklyn, NY, 5N/A, Scarsdale, NY
Purpose
Determine the efficacy of FoxHollow Silverhawk Atherectomy Device at obtaining a tissue diagnosis in the setting of malignant biliary strictures.
Materials & Methods
Eighty-one biopsies in seventy-nine patients with malignant biliary strictures underwent percutaneous biliary cholangiography. After cannulation of the biliary system, the Foxhollow Silverhawk device was used to obtain multiple biliary shavings, which were then sent for cytology and staining.Additional studies involving complex hepatobiliary and transplant cases were later included to determine this technique's utility in these clinical settings.
Results
A total of eighty-one biopsies were performed on seventy-nine patients after successful percutaneous transhepatic cholangiography and cannulation of the biliary system, using the Foxhollow Silverhawk Device. 39 of the participants were male while 40 were female. The participants also demonstrated an age range of 43-93 years, which corresponded to an average age of 70.6 years. A right approach to the biliary system was favored over the left at a rate of 77/81 or 95%.The results of this study yielded a sensitivity of 93% and a specificity of 100%. A positive predictive value of 100% and a negative predictive value of 64% were also demonstrated in this study. Of the false negative biopsies, all five were taken from the distal common bile duct. These false negatives were later diagnosed at surgery.
Conclusions
With a sensitivity of 93% and a specificity of 100%, the Foxhollow Silverhawk Atherectomy Device is a formidable option for tissue diagnosis in malignant biliary strictures.