SIR ePoster Library

Pneumothorax Rate Following Percutaneous CT-Guided Core Needle Biopsy of Lung Lesions: Improved Outcomes with Collagen Solution Tract Injection.
SIR ePoster library. Daruwalla V. 03/04/17; 169912; 476
Vistasp Daruwalla
Vistasp Daruwalla
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Abstract
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Final ID
476

Type
Original Scientific Research-Oral or Pos

Authors
V Daruwalla1, H YU2, H Kocharyan3, J Kallini4, P Lai5, J Koo6, K Patel6, M Le7, H Aoun6, J Critchfield8

Institutions
1Dmc/Wayne State University, Detroit, MI, 2DETROIT MEDICAL CENTER, WAYNE STATE UNIVERSITY, Novi, MI, 3DMC, Lansing, MI, 4Northwestern University, Chicago, IL, 5Wayne State University School of Medicine, Detroit, MI, 6Wayne State University, Detroit, MI, 7Detroit Medical Center/Wayne State University, Detroit, MI, 8N/A, Troy, MI

Purpose
To assess the pneumothorax rate of CT Guided lung biopsies with and without absorbable collagen solution injection post procedure along the biopsy tract.

Materials & Methods
A retrospective review of 200 consecutive patients who underwent CT guided lung biopsy between January 2014 and January 2016 by two experienced radiologists. All patients underwent CT guided core biopsies utilizing the coaxial technique consisting of a 19-G outer Trocar needle and a spring loaded 20-G inner cutting needle. 75 patients underwent biopsy tract collagen solution injection (BTCI) in which the operator injected Helitene® solution into the biopsy tract as the 19-G Trocar needle was removed. This was compared to a control group of 125 patients who underwent the standard biopsy procedure without collagen agent injection. The incidence of PTX on same day post procedural radiography was compared between the two groups. Other study parameters such as age, sex, chest wall distance, mass size, and smoking history were also compared between the two groups. Statistical analysis was performed by paired two tailed t-test.

Results
Our study population demonstrated that PTX occurred in 6 (8%) of 75 patients treated with BTCI, none of which required chest tube placement compared to 31 (24.8%) of the 125 control patients of which 9 (7%) required chest tube placement or other PTX management procedure. All the pneumothoraces (6) of BTCI group were small (<10%) and asymptomatic compared to the control group (31) of were mild to large (>20%) degree of PTX. There was a statistically significant (p>0.003) reduction in the incidence of PTX in the BTCI group compared to the control group. Although not statistically significant, there is also a considerable decrease in the number of chest tube placements and severity of the PTX as well. Other study parameters demonstrated no statistical significance difference between the two groups.

Conclusions
BTCI is a safe and a cost effective technique which significantly decreases the rates of PTX in patients undergoing CT guided core lung biopsies. It also reduces the number of chest tube placements and improves the severity of PTX. This technique should be considered in routine clinical practice.

Final ID
476

Type
Original Scientific Research-Oral or Pos

Authors
V Daruwalla1, H YU2, H Kocharyan3, J Kallini4, P Lai5, J Koo6, K Patel6, M Le7, H Aoun6, J Critchfield8

Institutions
1Dmc/Wayne State University, Detroit, MI, 2DETROIT MEDICAL CENTER, WAYNE STATE UNIVERSITY, Novi, MI, 3DMC, Lansing, MI, 4Northwestern University, Chicago, IL, 5Wayne State University School of Medicine, Detroit, MI, 6Wayne State University, Detroit, MI, 7Detroit Medical Center/Wayne State University, Detroit, MI, 8N/A, Troy, MI

Purpose
To assess the pneumothorax rate of CT Guided lung biopsies with and without absorbable collagen solution injection post procedure along the biopsy tract.

Materials & Methods
A retrospective review of 200 consecutive patients who underwent CT guided lung biopsy between January 2014 and January 2016 by two experienced radiologists. All patients underwent CT guided core biopsies utilizing the coaxial technique consisting of a 19-G outer Trocar needle and a spring loaded 20-G inner cutting needle. 75 patients underwent biopsy tract collagen solution injection (BTCI) in which the operator injected Helitene® solution into the biopsy tract as the 19-G Trocar needle was removed. This was compared to a control group of 125 patients who underwent the standard biopsy procedure without collagen agent injection. The incidence of PTX on same day post procedural radiography was compared between the two groups. Other study parameters such as age, sex, chest wall distance, mass size, and smoking history were also compared between the two groups. Statistical analysis was performed by paired two tailed t-test.

Results
Our study population demonstrated that PTX occurred in 6 (8%) of 75 patients treated with BTCI, none of which required chest tube placement compared to 31 (24.8%) of the 125 control patients of which 9 (7%) required chest tube placement or other PTX management procedure. All the pneumothoraces (6) of BTCI group were small (<10%) and asymptomatic compared to the control group (31) of were mild to large (>20%) degree of PTX. There was a statistically significant (p>0.003) reduction in the incidence of PTX in the BTCI group compared to the control group. Although not statistically significant, there is also a considerable decrease in the number of chest tube placements and severity of the PTX as well. Other study parameters demonstrated no statistical significance difference between the two groups.

Conclusions
BTCI is a safe and a cost effective technique which significantly decreases the rates of PTX in patients undergoing CT guided core lung biopsies. It also reduces the number of chest tube placements and improves the severity of PTX. This technique should be considered in routine clinical practice.

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